SIK2/3-IN-1
Product Specifications
CAS Number
3038863-24-7
Target
SIK
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
SIK2/3-IN-1 (Compound 7S) is an orally active and selective inhibitor of SIK2/3. It significantly inhibits tumor growth without causing weight loss in the MV4-11 AML mouse CDX model. SIK2/3-IN-1 is applicable for research in MEF2C-dependent acute myeloid leukemia.
Smiles
O=C1C=2C(=NC(=CC2CCN1CC(F)(F)F)C=3C=C(C=NC3N)C=4C=NN(C4)C)OC
Molecular Formula
C20H19F3N6O2
Molecular Weight
432.399
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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