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TTBK1/2-IN-2

Product Specifications

CAS Number

2857982-35-3

Target

Microtubule Associated

Related Pathways

Cytoskeletal Signaling

Bioactivity

TTBK1/2-IN-2 (compound 9) is a potent inhibitor of Tau tubulin kinase 1 (TTBK1) and TTBK2, with IC50 values of 384 nM and 175 nM, respectively. In human induced pluripotent stem cells (iPSC), TTBK1/2-IN-2 demonstrates a significant ciliogenesis phenotype.

Smiles

OC(C#CC=1C=CC=2NC3=C(C=4N=C(N=CC4CCC3)N)C2C1)(CC)CC

Molecular Formula

C22H24N4O

Molecular Weight

360.452

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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