What is the catalog number for CDD-2789?

The catalog number for CDD-2789 is T206617.

What sizes are available for CDD-2789?

CDD-2789 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does CDD-2789 come in?

CDD-2789 is available in 2 different pack sizes.

Is CDD-2789 in stock?

CDD-2789 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CDD-2789?

CDD-2789 is manufactured by Molfinity.

What is the estimated delivery time for CDD-2789?

Estimated delivery time for CDD-2789 is approximately 10 business day(s), depending on your location.

CDD-2789

Product Specifications

CAS Number

3052084-77-9

Target

TGF-beta/Smad, ALK

Related Pathways

Angiogenesis, Stem Cells, Tyrosine Kinase/Adaptors

Bioactivity

CDD-2789 is a highly selective small molecule inhibitor that targets Activin receptor type 1 (ALK2, also known as ACVR1) . It effectively blocks the BMP and activin A-induced downstream phosphorylation reactions by inhibiting the ALK2/ALK1-mediated SMAD1/5 signaling pathway. In the NanoBRET cell model, CDD-2789 demonstrates an inhibitory activity with an IC50 value of 0.54 μM for ALK2. This compound holds potential for research in ALK2-related diseases, including brainstem glioma (DIPG), ependymoma, endometrial cancer, melanoma, non-small cell lung cancer, colorectal cancer, and pancreatic cancer.