Decarbamoylmitomycin C
Product Specifications
CAS Number
26909-37-5
Target
MDM-2/p53, ATM/ATR
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair
Bioactivity
Decarbamoylmitomycin C, an analog of Mitomycin C (MC), functions as a DNA alkylating agent. It is capable of activating chromatin relaxation by the ataxia-telangiectasia and Rad3-related protein (ATR) in a p53-independent manner.
Smiles
O(C)[C@]12N(C3=C([C@H]1CO)C(=O)C(N)=C(C)C3=O)C[C@]4([C@@]2(N4)[H])[H]
Molecular Formula
C14H17N3O4
Molecular Weight
291.302
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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