Thalidomide-O-PEG1-OH
Product Specifications
CAS Number
2416234-31-4
Target
PROTAC Linker
Related Pathways
PROTAC
Bioactivity
Thalidomide-O-PEG1-OH is a PROTAC linker characterized by its combination of Thalidomide with O-ethyl. Thalidomide acts as a ligand for the E3 ubiquitin ligase, leading to protein ubiquitination and subsequent proteasomal degradation. Additionally, the hydroxy group serves as a versatile handle, facilitating the formation of more complex structures through various reactions.
Smiles
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCCO)C3C2=O)CC1
Molecular Formula
C15H14N2O6
Molecular Weight
318.281
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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