Mal-Val-Ala-PAB (C2-glucuronic acid) -DMEA-PNU-159682
Product Specifications
CAS Number
2682939-53-1
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
Mal-Val-Ala-PAB (C2-glucuronic acid) -DMEA-PNU-159682 is an active molecule-linker compound used in ADCs, consisting of a cleavable Val-Ala linker and the potent ADC cytotoxin PNU-159682.
Smiles
O([C@@H]1C2=C(C(O)=C3C(=C2O)C(=O)C=4C(C3=O)=CC=CC4OC)C[C@](C(COC(N(CCN(C(OCC5=C(CC[C@@H]6O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]6O)C=C(NC([C@@H](NC([C@@H](NC(CN7C(=O)C=CC7=O)=O)[C@@H](C)C)=O)C)=O)C=C5)=O)C)C)=O)=O)(O)C1)[C@H]8C[C@@]9(N%10[C@](O[C@@]9([C@H](C)O8)[H])([C@@H](OC)OCC%10)[H])[H]
Molecular Formula
C67H81N7O27
Molecular Weight
1416.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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