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BMS-986238

Product Specifications

CAS Number

2919596-13-5

Target

PD-1/PD-L1

Related Pathways

Immunology/Inflammation, Cell Cycle/Checkpoint, Apoptosis

Bioactivity

BMS-986238 is a second-generation macrocyclic peptide and an effective PD-L1 inhibitor. It holds potential for research in the treatment of solid tumors and lymphomas (cancer of the lymphatic system) .

Smiles

C(C=1C=2C(N(CC(O)=O)C1)=CC=CC2)[C@H]3C(=O)N(C)[C@@H](CCCC)C(=O)N(C)[C@@H](CCCC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(NCC(N[C@@H](CC4=CN(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CC[C@H](NC(CCCCCCCCCCCCCCCCC(O)=O)=O)C(O)=O)=O)N=N4)C(O)=O)=O)=O)CSCC(=O)N[C@@H](CC5=CC=C(O)C=C5)C(=O)N(C)[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N6[C@](C(=O)N[C@@H](CN)C(=O)N[C@@H](CC(C)C)C(=O)N7[C@](C(=O)N[C@@H](CC=8C=9C(NC8)=CC=CC9)C(=O)N[C@@H](CCN)C(=O)N3)(C[C@@H](O)C7)[H])(CCC6)[H]

Molecular Formula

C143H224N26O40S

Molecular Weight

2979.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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