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(Rac) -Roscovitine

Product Specifications

CAS Number

186692-44-4

Target

CDK, Apoptosis

Related Pathways

Cell Cycle/Checkpoint, Apoptosis

Bioactivity

(Rac) -Roscovitine ((Rac) -Seliciclib) is a selective inhibitor of cyclin-dependent kinases (CDKs) . It competes with ATP for binding at the active site of CDKs, thereby inhibiting their phosphorylation activity. This compound induces apoptosis in cancer cells and holds potential for the study of conditions like cancer, neurodegenerative diseases, heart diseases, viral and protozoal infections, glomerulonephritis, and chronic inflammation, all of which are associated with CDK dysregulation.

Smiles

OCC(NC=1N=C(NCC=2C=CC=CC2)C=3N=CN(C3N1)C(C)C)CC

Molecular Formula

C19H26N6O

Molecular Weight

354.449

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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