PPAR? agonist 5
Product Specifications
Target
Phosphatase|||PPAR
Related Pathways
DNA Damage/DNA Repair|||Metabolism
Bioactivity
PPAR? agonist5 is an orally active, selective partial agonist of PPAR? with an EC50 of 3 nM. It reduces lipid accumulation and upregulates PPAR? target genes, exhibiting anti-hepatic steatosis properties. Additionally, PPAR? agonist5 demonstrates significant lipid-lowering and glucose-lowering effects through partial PPAR? agonist activity and mild inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 79.1 ?M. It has favorable safety and is applicable in the study of dyslipidemia in type 2 diabetes.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/348162709910454277/T206549
Available Sizes
Curated Selection
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