Metahexestrol
Product Specifications
CAS Number
71953-72-5
Target
Estrogen Receptor/ERR
Related Pathways
Endocrinology/Hormones
Bioactivity
Metahexestrol is an inhibitor of the estrogen receptor (E2R) with antitumor activity. It significantly inhibits the proliferation of estrogen receptor-positive MCF-7 human breast cancer cell line with an ED50 of 1.0 μM. Additionally, Metahexestrol shows inhibitory activity in estrogen receptor-negative MDA-MB-231 cell lines, and its antiproliferative effect is not reversed by estrogen, suggesting that its mechanism may be partially independent of the E2R pathway. Metahexestrol is applicable in research on estrogen-dependent breast cancer.
Smiles
[C@H]([C@H](CC)C1=CC(O)=CC=C1)(CC)C2=CC(O)=CC=C2
Molecular Formula
C18H22O2
Molecular Weight
270.366
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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