MIDD0301 sodium
Product Specifications
CAS Number
2593569-36-7
Target
GABA Receptor
Related Pathways
Neuroscience|||Membrane transporter/Ion channel
Bioactivity
MIDD0301 (GL-II-93) sodium is an orally active inhibitor of ?-aminobutyric acid type A receptors (GABAAR) and an anti-asthmatic agent. It shows bio- and immunotoxicological safety in mice without affecting circulating lymphocyte, monocyte, and granulocyte counts. MIDD0301 sodium demonstrates no significant adverse immune responses under repeated dosing and is more favorable than Prednisone. It relaxes histamine-contracted tracheal smooth muscle in guinea pigs and humans, making it a valuable candidate for research in bronchoconstriction-related diseases.
Smiles
C(O)(=O)C1=C2N(C=3C(C(=N[C@@H]2C)C4=C(F)C=CC=C4)=CC(Br)=CC3)C=N1.[Na]
Molecular Formula
C19H13BrFN3NaO2
Molecular Weight
437.218
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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