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MIDD0301 sodium

Product Specifications

CAS Number

2593569-36-7

Target

GABA Receptor

Related Pathways

Neuroscience|||Membrane transporter/Ion channel

Bioactivity

MIDD0301 (GL-II-93) sodium is an orally active inhibitor of ?-aminobutyric acid type A receptors (GABAAR) and an anti-asthmatic agent. It shows bio- and immunotoxicological safety in mice without affecting circulating lymphocyte, monocyte, and granulocyte counts. MIDD0301 sodium demonstrates no significant adverse immune responses under repeated dosing and is more favorable than Prednisone. It relaxes histamine-contracted tracheal smooth muscle in guinea pigs and humans, making it a valuable candidate for research in bronchoconstriction-related diseases.

Smiles

C(O)(=O)C1=C2N(C=3C(C(=N[C@@H]2C)C4=C(F)C=CC=C4)=CC(Br)=CC3)C=N1.[Na]

Molecular Formula

C19H13BrFN3NaO2

Molecular Weight

437.218

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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