MJ210
Product Specifications
Target
NF-?B|||Reactive Oxygen Species|||p38 MAPK|||ROS
Related Pathways
MAPK|||Metabolism|||NF-?B|||Immunology/Inflammation
Bioactivity
MJ210 is an orally active and blood-brain barrier-permeable modulator of the NF-?B and MAPK pathways, exhibiting neuroprotective properties. In vitro, 5 ?M MJ210 can increase the survival rate of rotenone-treated SH-SY5Y cells to 81.9% and reduce levels of ROS. In vivo, 5 mg/kg MJ210 improves motor dysfunction in rat models of Parkinson's disease. MJ210 is useful for research in neurological disorders, including Parkinson's disease.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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