NK7-902
Product Specifications
Target
MAPK
Related Pathways
MAPK
Bioactivity
NK7-902 is a CRBN molecular glue degrader of NEK7. It fully degrades NEK7 in human primary monocytes and whole blood, yet only partially inhibits NLRP3-dependent IL-1? production. NK7-902 results in profound and lasting degradation of NEK7, but only temporarily blocks NLRP3 inflammasome activation in non-human primates via oral administration. The compound demonstrates activity in mouse systems.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15110538 1 Vial
Lentiviral mouse Mllt11 shRNA (UAS) - Lentiviral mouse Mllt11 shRNA (UAS) (100)
Ask
View Details