What is the catalog number for Antitumor agent-200?

The catalog number for Antitumor agent-200 is T206452.

What sizes are available for Antitumor agent-200?

Antitumor agent-200 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does Antitumor agent-200 come in?

Antitumor agent-200 is available in 2 different pack sizes.

Is Antitumor agent-200 in stock?

Antitumor agent-200 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Antitumor agent-200?

Antitumor agent-200 is manufactured by Molfinity.

What is the estimated delivery time for Antitumor agent-200?

Estimated delivery time for Antitumor agent-200 is approximately 10 business day(s), depending on your location.

Antitumor agent-200

Product Specifications

CAS Number

3046118-64-0

Target

Microtubule Associated, P-gp

Related Pathways

Cytoskeletal Signaling, Neuroscience, Membrane transporter/Ion channel

Bioactivity

Antitumor agent-200 (Compound 2g) is a microtubule synthesis inhibitor that binds to the colchicine site on tubulin, causing G2/M cell cycle arrest and inducing reactive oxygen species (ROS) production. It demonstrates significant inhibitory activity against P-glycoprotein (P-gp) overexpressing cell lines MCF7/ADR and KBV200, with resistance indices (DRI) of 0.83 and 0.58, respectively. In an MCF-7 xenograft model, Antitumor agent-200 (at 25 mg/kg, administered intraperitoneally) achieves a 57.2% tumor growth inhibition rate. This compound is applicable for research in the field of cancer therapy.