Thalidomide-pinacolborane
Product Specifications
CAS Number
2229725-98-6
Target
Ligand for E3 Ligase
Related Pathways
PROTAC
Bioactivity
Thalidomide-pinacolborane is a Thalidomide analogue featuring a boronic acid pinacol ester, also known as a Bpin group, commonly used in Suzuki reactions. The molecule acts as an activator of E3 ligase, facilitating the ubiquitination of proteins, thereby targeting them for proteolytic degradation.
Smiles
O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)B4OC(C)(C)C(O4)(C)C
Molecular Formula
C19H21BN2O6
Molecular Weight
384.191
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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