LPT99
Product Specifications
CAS Number
1263477-83-3
Target
Apoptosis, Caspase
Related Pathways
Apoptosis, Proteases/Proteasome
Bioactivity
LPT-99 is an antagonist of the apoptosis protease-activating factor 1 (APAF-1) . It inhibits the activation of procaspase-9 and can suppress apoptosis induced by Cisplatin. Additionally, LPT-99 effectively reduces Cisplatin-induced hearing loss in rats.
Smiles
O=C(NCCC1=CNC=2C=CC(OC)=CC21)CC3C(=O)N(CC(=O)N3CCC=4SC=CC4)CCC5=CC=C(Cl)C=C5Cl
Molecular Formula
C31H32Cl2N4O4S
Molecular Weight
627.581
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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