UNC10013
Product Specifications
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
UNC10013 is an allosteric modulator of SETDB1, exhibiting negative allosteric regulation through covalent bond formation with Cys385 on the 3TD domain. It has a kinact/KI value of 1.0 x 10^6 M^-1*s^-1. UNC10013 effectively disrupts SETDB1-mediated Akt methylation, holding potential for application in cancer and neurodegenerative disease research.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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