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(S, R, S) -AHPC-PEG2-NHS ester

Product Specifications

CAS Number

2757045-58-0

Target

PROTAC Linker

Related Pathways

PROTAC

Bioactivity

(S, R, S) -AHPC-PEG2-NHS ester is a synthetic PROTAC linker that combines the E3 ligase ligand with a PEG linker to enhance PROTAC pharmacology. The NHS ester reacts with amine groups, and the hydrophilic PEG spacer increases water solubility.

Smiles

C(C(NC(CCOCCOCCC(ON1C(=O)CCC1=O)=O)=O)C(C)(C)C)(=O)N2[C@H](C(NCC3=CC=C(C=C3)C=4SC=NC4C)=O)C[C@@H](O)C2

Molecular Formula

C34H45N5O10S

Molecular Weight

715.814

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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