What is the catalog number for Akt1-IN-8?

The catalog number for Akt1-IN-8 is T206415.

What sizes are available for Akt1-IN-8?

Akt1-IN-8 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does Akt1-IN-8 come in?

Akt1-IN-8 is available in 2 different pack sizes.

Is Akt1-IN-8 in stock?

Akt1-IN-8 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Akt1-IN-8?

Akt1-IN-8 is manufactured by Molfinity.

What is the estimated delivery time for Akt1-IN-8?

Estimated delivery time for Akt1-IN-8 is approximately 10 business day(s), depending on your location.

Akt1-IN-8

Product Specifications

CAS Number

2247688-87-3

Target

Akt

Related Pathways

Cytoskeletal Signaling, PI3K/Akt/mTOR signaling

Bioactivity

Akt1-IN-8 (Compound JL18) is a potent AKT1 kinase inhibitor with oral bioavailability of 41% and an IC50 value of 8.8 nM. It exhibits significant antiproliferative effects against PC-3 prostate cancer cells, with an IC50 of 3.0 μM. Akt1-IN-8 also reduces phosphorylated GSK3β levels.