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5- (2-Chloroacetamide) thalidomide

Product Specifications

CAS Number

1957235-51-6

Target

Ligand for E3 Ligase

Related Pathways

PROTAC

Bioactivity

5- (2-Chloroacetamide) thalidomide is an analog of Thalidomide. Thalidomide functions by recruiting E3 ligase for ubiquitination, leading to the degradation of specific proteins. This compound features a chloroacetamide moiety, which acts as a thiol-specific reactive group.

Smiles

O=C(NC1=CC=C2C(=O)N(C(=O)C2=C1)C3C(=O)NC(=O)CC3)CCl

Molecular Formula

C15H12ClN3O5

Molecular Weight

349.726

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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