EIF4E-IN-4
Product Specifications
CAS Number
1373822-39-9
Target
PERK
Related Pathways
Apoptosis
Bioactivity
EIF4E-IN-4 (Compound 33) is a selective inhibitor of the eukaryotic initiation factor 4E (eIF4E) with a biochemical activity value of 95 nM. It inhibits cap-dependent mRNA translation with an IC50 of 2.5 μM and is applicable in research on breast cancer, colon cancer, and head and neck cancer.
Smiles
O=C1N=C(NC=2N=C(C=3C=CC(=CC3)P(=O)(O)O)N(C12)CCOC4=CC=C(Cl)C=C4)NC
Molecular Formula
C20H19ClN5O5P
Molecular Weight
475.822
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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