Thalidomide-4-carbaldehyde
Product Specifications
CAS Number
2369068-46-0
Target
Ligand for E3 Ligase
Related Pathways
PROTAC
Bioactivity
Thalidomide-4-carbaldehyde is a thalidomide analogue that contains an aldehyde group. Thalidomide recruits E3 ligases for ubiquitination, leading to proteolysis of target proteins. The aldehyde is highly reactive with amine nucleophiles via reactions like reductive amination.
Smiles
O=CC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
Molecular Formula
C14H10N2O5
Molecular Weight
286.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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