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Thalidomide-4-carbaldehyde

Product Specifications

CAS Number

2369068-46-0

Target

Ligand for E3 Ligase

Related Pathways

PROTAC

Bioactivity

Thalidomide-4-carbaldehyde is a thalidomide analogue that contains an aldehyde group. Thalidomide recruits E3 ligases for ubiquitination, leading to proteolysis of target proteins. The aldehyde is highly reactive with amine nucleophiles via reactions like reductive amination.

Smiles

O=CC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3

Molecular Formula

C14H10N2O5

Molecular Weight

286.24

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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