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Thalidomide-5-Br,6-F

Product Specifications

CAS Number

2803445-69-2

Target

Ligand for E3 Ligase

Related Pathways

PROTAC

Bioactivity

Thalidomide-5-Br,6-F is an analog of Thalidomide and acts as an E3 ligase activator. It facilitates the ubiquitination of proteins to promote proteolysis. The structure allows for further derivatization by substituting fluorine or bromine.

Smiles

O=C1NC(=O)C(N2C(=O)C3=CC(F)=C(Br)C=C3C2=O)CC1

Molecular Formula

C13H8BrFN2O4

Molecular Weight

355.116

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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