Thalidomide-5-Br,6-F
Product Specifications
CAS Number
2803445-69-2
Target
Ligand for E3 Ligase
Related Pathways
PROTAC
Bioactivity
Thalidomide-5-Br,6-F is an analog of Thalidomide and acts as an E3 ligase activator. It facilitates the ubiquitination of proteins to promote proteolysis. The structure allows for further derivatization by substituting fluorine or bromine.
Smiles
O=C1NC(=O)C(N2C(=O)C3=CC(F)=C(Br)C=C3C2=O)CC1
Molecular Formula
C13H8BrFN2O4
Molecular Weight
355.116
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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