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MAGL-IN-222

Product Specifications

CAS Number

877804-65-4

Target

Lipase

Related Pathways

Metabolism

Bioactivity

MAGL-IN-222 (Compound ZQ-7) is a covalent inhibitor that targets monoacylglycerol lipase (MAGL), with an IC50 of 42.31 ?M. It reduces the breakdown of 2-arachidonoylglycerol (2-AG), enhancing intracellular 2-AG levels, thereby inhibiting the proliferation and migration of MDA-MB-231 breast cancer cells. MAGL-IN-222 is applicable in breast cancer research and related diseases.

Smiles

N#CC=1C(=O)N(C(=O)C(=CC2=CC=C(C=C2)N(CC)CC)C1C)C3CCS(=O)(=O)C3

Molecular Formula

C22H25N3O4S

Molecular Weight

427.517

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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