MAGL-IN-222
Product Specifications
CAS Number
877804-65-4
Target
Lipase
Related Pathways
Metabolism
Bioactivity
MAGL-IN-222 (Compound ZQ-7) is a covalent inhibitor that targets monoacylglycerol lipase (MAGL), with an IC50 of 42.31 ?M. It reduces the breakdown of 2-arachidonoylglycerol (2-AG), enhancing intracellular 2-AG levels, thereby inhibiting the proliferation and migration of MDA-MB-231 breast cancer cells. MAGL-IN-222 is applicable in breast cancer research and related diseases.
Smiles
N#CC=1C(=O)N(C(=O)C(=CC2=CC=C(C=C2)N(CC)CC)C1C)C3CCS(=O)(=O)C3
Molecular Formula
C22H25N3O4S
Molecular Weight
427.517
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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