P131
Product Specifications
CAS Number
2360561-66-4
Target
PROTAC Linker
Related Pathways
PROTAC
Bioactivity
P131 is a PROTAC molecule consisting of a cereblon ligand based on Pomalidomide and IBT6A, linked via a PEG linker. P131 effectively degrades both wild-type and C481S mutant BTK with nanomolar potency.
Smiles
NC1=C2C(N(N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)[C@H]5CN(C(=O)C6=CN(CCOCCOCCOCCNC7=C8C(C(=O)N(C8=O)C9C(=O)NC(=O)CC9)=CC=C7)N=N6)CCC5)=NC=N1
Molecular Formula
C46H48N12O9
Molecular Weight
912.948
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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