SMW139
Product Specifications
CAS Number
2133010-38-3
Target
P2X Receptor, Interleukin
Related Pathways
Immunology/Inflammation, Neuroscience, Membrane transporter/Ion channel
Bioactivity
SMW139 is a selective allosteric antagonist of the P2X7 receptor, exhibiting a Ki value of 32 nM for human P2X7R. In rat liver microsomes, its half-life is 47 minutes. SMW139 is applicable in research related to inflammation, Alzheimer's disease, and multiple sclerosis.
Smiles
O=C(NCC12CC3(F)CC(F)(CC(F)(C3)C1)C2)C4=CC(OC)=CC=C4Cl
Molecular Formula
C19H21ClF3NO2
Molecular Weight
387.824
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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