YJZ5118
Product Specifications
CAS Number
3031861-18-1
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
YJZ5118 is a CDK12/13 inhibitor, possessing IC50 values of 39.5 nM and 26.4 nM for CDK12 and CDK13, respectively. This compound can inhibit tumor cell proliferation by inducing DNA damage and apoptosis (Apoptosis) and exhibits a synergistic effect with Akt inhibitors. YJZ5118 is applicable in cancer research.
Smiles
N(C(NCC1=CC=CC=C1)=O)(C2=CC(NC(C=C)=O)=C(C=C2)N3CCC(N(C)C)CC3)[C@@H]4CC[C@@H](NC5=CC=C(C#N)C=N5)CC4
Molecular Formula
C36H44N8O2
Molecular Weight
620.787
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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