Dirozalkib
Product Specifications
CAS Number
1893419-37-8
Target
ALK
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
Dirozalkib (Compound 4) is an ALK inhibitor with an IC50 of 0.9 nM. It demonstrates antiproliferative activity in cancer cells NCI-H3122, Karpas-299, and NCI-H2228, with IC50 values of 130.4, 0.71, and 15.11 nM, respectively. Dirozalkib exhibits favorable pharmacokinetic properties and a bioavailability ranging from 30% to 50%.
Smiles
O=S(=O)(C=1C=CC=CC1NC2=NC(=NC=C2Cl)NC=3C=C(C(=C4OCCOC43)C5CCNCC5)C)C(C)C
Molecular Formula
C27H32ClN5O4S
Molecular Weight
558.092
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Recombinant Babesia bovis Superoxide dismutase [Fe] (SODB)](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
MBS1162981-01 0.02 mg (E-Coli)
Recombinant Babesia bovis Superoxide dismutase [Fe] (SODB)
Sign In for Pricing
View Details MBS1162981-02 0.1 mg (E-Coli)
Recombinant Babesia bovis Superoxide dismutase [Fe] (SODB)
Sign In for Pricing
View Details MBS1162981-03 0.02 mg (Yeast)
Recombinant Babesia bovis Superoxide dismutase [Fe] (SODB)
Sign In for Pricing
View Details MBS1162981-04 0.1 mg (Yeast)
Recombinant Babesia bovis Superoxide dismutase [Fe] (SODB)
Sign In for Pricing
View Details MBS1162981-05 0.02 mg (Baculovirus)
Recombinant Babesia bovis Superoxide dismutase [Fe] (SODB)
Sign In for Pricing
View Details MBS1162981-06 0.02 mg (Mammalian-Cell)
Recombinant Babesia bovis Superoxide dismutase [Fe] (SODB)
Sign In for Pricing
View Details