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STING-IN-12

Product Specifications

Target

STING

Related Pathways

Immunology/Inflammation

Bioactivity

STING-IN-12 (compound Y2) acts as an inhibitor of STING. It suppresses IFNβ gene expression induced by SR717 with an IC50 of 0.75 μM. Additionally, STING-IN-12 inhibits STING pathway activation induced by the STING agonist SR717 in THP1 cells and by MSA-2 in mice.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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