5-LOX-IN-8
Product Specifications
Target
TNF, IFNAR, Lipoxygenase, Interleukin
Related Pathways
Immunology/Inflammation, Metabolism, Apoptosis
Bioactivity
5-LOX-IN-8 is a 5-LOX inhibitor with anti-inflammatory properties. It suppresses IL-6, IL-1β, TNF-α, and IFN-γ in macrophages and reduces IL-8 secretion in SW480 cells. Additionally, 5-LOX-IN-8 decreases the disease activity index in DSS colitis models. This compound is applicable for research in inflammatory bowel disease (IBD) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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