RIP1-IN-1
Product Specifications
Target
Necroptosis, RIP kinase
Related Pathways
NF-κB, Apoptosis
Bioactivity
RIP1-IN-1 is an orally bioavailable RIP1 inhibitor with a high binding affinity (Kd: 110 nM) . This compound exhibits significant activity against necroptosis and effectively suppresses necrosome formation by inhibiting the phosphorylation of RIP1, RIP3, and MLKL pathways. RIP1-IN-1 can inhibit necroptosis and is applicable in research on acute liver injury.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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