ASK1-IN-8
Product Specifications
CAS Number
2570985-89-4
Target
ASK
Related Pathways
Apoptosis
Bioactivity
ASK1-IN-8 (Compound 35) is an orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 value of 1.8 nM. In a mouse liver injury model induced by Acetaminophen, ASK1-IN-8 significantly reduces plasma alanine aminotransferase (ALT) levels, offering liver protection. This compound is useful for research in liver disease-related fields.
Smiles
O=C1N(C2=NC(=CC=C2)C3=NN=CN3C(C)C)CCN1C4=CC=C(C=C4)N5CCC(C(=O)NC)CC5
Molecular Formula
C26H32N8O2
Molecular Weight
488.585
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
033681 200 µL
Cdk7, phosphorylated (T170) (STK1, p39 Mo15, 39kD protein kinase, TFIIH basal transcription factor complex kinase subunit, CAK1, CDK-activating kinase, CAK, Cell division protein kinase 7, MO15, CDK7)
Sign In for Pricing
View Details 
MBS2544455-01 0.06 mL
Rabbit anti Mouse LY86/MD-1 Monoclonal Antibody
Sign In for Pricing
View Details