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Pyrazole N-Desmethyl sildenafil

Product Specifications

CAS Number

139755-95-6

Target

Parasite|||PDE

Related Pathways

Microbiology/Virology|||Metabolism

Bioactivity

Pyrazole N-Desmethyl sildenafil (Compound 10) is an analogue of Sildenafil. At a concentration of 100 µM, it inhibits the activity of the Trypanosoma brucei phosphodiesterase TbrPDEB1 by 16%.

Smiles

CCCc1[nH]nc2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1

Molecular Formula

C21H28N6O4S

Molecular Weight

460.55

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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