What is the catalog number for Hyp-dBET1?

The catalog number for Hyp-dBET1 is T206198.

What sizes are available for Hyp-dBET1?

Hyp-dBET1 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does Hyp-dBET1 come in?

Hyp-dBET1 is available in 2 different pack sizes.

Is Hyp-dBET1 in stock?

Hyp-dBET1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Hyp-dBET1?

Hyp-dBET1 is manufactured by Molfinity.

What is the estimated delivery time for Hyp-dBET1?

Estimated delivery time for Hyp-dBET1 is approximately 10 business day(s), depending on your location.

Hyp-dBET1

Product Specifications

Target

Epigenetic Reader Domain, PROTACs

Related Pathways

PROTAC, Chromatin/Epigenetic

Bioactivity

Hyp-dBET1 is a PROTAC degrader targeting BRD4, with an IC50 value of 3.4 μM in MDA-MB-231 cells. Under hypoxic conditions, Hyp-dBET1 becomes active, recruiting E3 ubiquitin ligase, and facilitates the degradation of BRD4 via the ubiquitin-proteasome system. Hyp-dBET1 is applicable in anti-cancer research.