5-Hydroxy-2- (1-methyl-2,6-dioxopiperidin-3-yl) isoindole-1,3-dione
Product Specifications
CAS Number
2589697-74-3
Target
Ligand for E3 Ligase
Related Pathways
PROTAC
Bioactivity
5-Hydroxy-2- (1-methyl-2,6-dioxopiperidin-3-yl) isoindole-1,3-dione is a Thalidomide analog featuring a hydroxyl group, which serves as a versatile site for further derivatization. Thalidomide acts as an E3 ligase activator and facilitates the ubiquitination of specific proteins.
Smiles
O=C1C2=CC=C(O)C=C2C(=O)N1C3C(=O)N(C(=O)CC3)C
Molecular Formula
C14H12N2O5
Molecular Weight
288.255
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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