JZ19
Product Specifications
Target
Apoptosis, Akt, PI3K, GSK-3
Related Pathways
Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Stem Cells, Apoptosis
Bioactivity
JZ19 reduces intracellular levels of LDH and ROS and demonstrates antioxidant activity against oxygen-glucose deprivation (OGD) -induced myocardial cell damage. It reverses Isoproterenol-induced myocardial cell hypertrophy and apoptosis through the PI3K-AKT-GSK3β signaling pathway. Additionally, JZ19 alleviates Isoproterenol-induced heart failure in mouse models.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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