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JZ19

Product Specifications

Target

Apoptosis, Akt, PI3K, GSK-3

Related Pathways

Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Stem Cells, Apoptosis

Bioactivity

JZ19 reduces intracellular levels of LDH and ROS and demonstrates antioxidant activity against oxygen-glucose deprivation (OGD) -induced myocardial cell damage. It reverses Isoproterenol-induced myocardial cell hypertrophy and apoptosis through the PI3K-AKT-GSK3β signaling pathway. Additionally, JZ19 alleviates Isoproterenol-induced heart failure in mouse models.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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