BMY 7378 free base
Product Specifications
CAS Number
21102-94-3
Target
Adrenergic Receptor, 5-HT Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
BMY 7378 (free base) is a selective antagonist for the α1D adrenergic receptor (α1D-AR) . It exhibits a membrane-binding affinity for cloned rat α1D-AR (Ki=2 nM) that is over 100 times stronger than its affinity for cloned rat α1A-AR (Ki=800 nM) or hamster α1B-AR (Ki=600 nM) . Additionally, BMY 7378 (free base) acts as a partial agonist at the 5-HT1A receptor.
Smiles
O=C1N(C(=O)CC2(C1)CCCC2)CCN3CCN(C=4C=CC=CC4OC)CC3
Molecular Formula
C22H31N3O3
Molecular Weight
385.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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