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EGFR-IN-146

Product Specifications

CAS Number

166039-38-9

Target

AMPK, EGFR

Related Pathways

Angiogenesis, JAK/STAT signaling, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling

Bioactivity

EGFR-IN-146 is an EGFR inhibitor that suppresses the EGFR signaling pathway and improves insulin sensitivity by activating the AMPK pathway. It effectively reduces blood glucose levels and body weight, showing great potential in the study of diabetes and obesity.

Smiles

N=1C=CC=C(C1)CNC=2N=C(N=C3C=CC=CC32)C=4C=CC=CC4

Molecular Formula

C20H16N4

Molecular Weight

312.368

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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