EGFR-IN-146
Product Specifications
CAS Number
166039-38-9
Target
AMPK, EGFR
Related Pathways
Angiogenesis, JAK/STAT signaling, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling
Bioactivity
EGFR-IN-146 is an EGFR inhibitor that suppresses the EGFR signaling pathway and improves insulin sensitivity by activating the AMPK pathway. It effectively reduces blood glucose levels and body weight, showing great potential in the study of diabetes and obesity.
Smiles
N=1C=CC=C(C1)CNC=2N=C(N=C3C=CC=CC32)C=4C=CC=CC4
Molecular Formula
C20H16N4
Molecular Weight
312.368
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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