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Thalidomide-5-carbaldehyde

Product Specifications

CAS Number

1447701-63-4

Target

Ligand for E3 Ligase

Related Pathways

PROTAC

Bioactivity

Thalidomide-5-carbaldehyde is an aldehyde-containing analogue of Thalidomide. Thalidomide recruits E3 ligase for ubiquitination, leading to proteolysis of target proteins. The aldehyde group exhibits high reactivity towards amine nucleophiles through reactions such as reductive amination.

Smiles

O=CC1=CC=C2C(=O)N(C(=O)C2=C1)C3C(=O)NC(=O)CC3

Molecular Formula

C14H10N2O5

Molecular Weight

286.24

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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