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(S, R, S) -AHPC-PEG6-Tos

Product Specifications

CAS Number

2839806-94-7

Target

E3 Ligase Ligand-Linker Conjugate

Related Pathways

PROTAC

Bioactivity

(S, R, S) -AHPC-PEG6-Tos is a compound combining a VHL recruiter ligand and a polyethylene glycolated crosslinker with a tosyl group. The tosyl group serves as a good leaving group in nucleophilic substitution reactions. (S, R, S) -AHPC-PEG2-Tos is applicable in the synthesis of PROTAC compounds and for molecules designed for targeted protein degradation.

Smiles

C([C@@H](NC(CCOCCOCCOCCOCCOCCOS(=O)(=O)C1=CC=C(C)C=C1)=O)[C@](C)(C)C)(=O)N2[C@H](C(NCC3=CC=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2

Molecular Formula

C42H60N4O12S2

Molecular Weight

877.075

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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