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(S, R, S) -AHPC-PEG4-NHS ester

Product Specifications

CAS Number

2757045-59-1

Target

PROTAC Linker

Related Pathways

PROTAC

Bioactivity

(S, R, S) -AHPC-PEG4-NHS ester is a PROTAC linker that fuses an E3 ligase ligand with a PEG4 spacer, enhancing PROTAC drug chemistry. It reacts with amine molecules, and the inclusion of the PEG4 arm improves the solubility of the molecule.

Smiles

C(C(NC(CCOCCOCCOCCOCCC(ON1C(=O)CCC1=O)=O)=O)C(C)(C)C)(=O)N2[C@H](C(NCC3=CC=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2

Molecular Formula

C38H53N5O12S

Molecular Weight

803.919

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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