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AKT1-IN-9

Product Specifications

Target

Akt

Related Pathways

PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling

Bioactivity

AKT1-IN-9 (4) is a selective inhibitor of the AKT1 (E17K) mutation, exhibiting EC50 values of 9 nM in LAPC4-CR cells and 995 nM in SkBr3 cells.

Smiles

NC1=NC=CC=C1C2=NC3=C(N=C(C4=CC=CC=C4)C=C3)N2C5=CC=C(CNC(CC6=CC=C(C(O)=O)C(O)=C6F)=O)C=C5

Molecular Formula

C33H25FN6O4

Molecular Weight

588.588

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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