AKT1-IN-9
Product Specifications
Target
Akt
Related Pathways
PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling
Bioactivity
AKT1-IN-9 (4) is a selective inhibitor of the AKT1 (E17K) mutation, exhibiting EC50 values of 9 nM in LAPC4-CR cells and 995 nM in SkBr3 cells.
Smiles
NC1=NC=CC=C1C2=NC3=C(N=C(C4=CC=CC=C4)C=C3)N2C5=CC=C(CNC(CC6=CC=C(C(O)=O)C(O)=C6F)=O)C=C5
Molecular Formula
C33H25FN6O4
Molecular Weight
588.588
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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