Val-Ala-PAB-SN38
Product Specifications
CAS Number
3025787-76-9
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
Val-Ala-PAB-SN38 is a drug-linker conjugate for ADCs, comprising the ADC linker Val-Ala-PAB and SN38. SN-38 is the active metabolite of irinotecan, which acts as an inhibitor of topoisomerase I (TopoisomeraseI) .
Smiles
O=C1N2C(C=3C(C2)=C(CC)C=4C(N3)=CC=C(O)C4)=CC5=C1COC(=O)[C@]5(OC(OCC6=CC=C(NC([C@@H](NC([C@H](C(C)C)N)=O)C)=O)C=C6)=O)CC
Molecular Formula
C38H41N5O9
Molecular Weight
711.76
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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