KRASG12D-IN-3-d3
Product Specifications
CAS Number
3033638-69-3
Target
Ras, Kras
Related Pathways
MAPK
Bioactivity
KRASG12D-IN-3-d3 is the deuterium labeled KRASG12D-IN-3. KRASG12D-IN-3 (compound Z1084) is a KRASG12D inhibitor with oral bioactivity that can effectively inhibit the growth of tumor cells AGS and AsPC-1, with IC50 values of 0.38 nM and 1.23 nM, respectively.
Smiles
ClC1=C(C(F)(F)F)C(C2=C(F)C(N=C(OC[C@]3(C/C(C4)=C(F)\F)N4CCC3)N=C5N(C[C@@H]6N[C@H]7CC6)[C@@H]7[C@H](C([2H])([2H])[2H])O8)=C5C8=N2)=CC(N)=C1
Molecular Formula
C31H27D3ClF6N7O2
Molecular Weight
685.08
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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